Transdermal Drug Delivery System


transdermal_display_img

Keuntungan:

  • kadar obat dalam darah konstan, mencegah fluktuasi

  • menghindari first pass effect metabolism di hati

  • mengurangi frekuensi pemberian obat (ada patch yang dapat digunakan selama 7 hari)

  • patch tidak mengiritasi dan penggunaan patch dapat dihentikan dengan mudah

mudah digunakan dan dimonitor

 

No Nama Zat Nama Produk Jenis Patch Indikasi Frekuensi
1 Clonidin Catapres-TTS® Hipertensi
2 Ethinylestradiol (EO) dan norelgestromin (N) Ortho-Evra® Drug-in-adhesive Kontrasepsi Per-minggu
3 Fentanyl Duragesic® Drug-in-adhesive Analgesik Per-minggu
4 Lidocain Lidoderm® Reservoir Nalgesia untuk postherpetic neuralgia (PHN) dan sakit akibat virus varicella zoster Per-hari
5 Nikotin Habitrol®, Nicoderm-HQ ®, Nicotrol ®, Postrep® Kecanduan merokok Per-hari
6 Nitrogliserin Nitro-Dur®, Transderm-Nitro® Drug-in-adhesive,

Reservoir (Nitrodisc)

Angina Per-hari
7 Estradiol Alora®, Climara®, Esclim®, Estraderm® Drug-in-adhesive Pengganti hormon Per-minggu
8 Estradiol +Norethindrone CombiPatch® Pengganti hormon
9 Oxybutynin Oxytrol® Drug-in-adhesive Antispasmodik 2x seminggu
10 Scopolamin Transderm Scop® Motionsickness
11 Testosteron Androderm®, Testoderm TTS®, Testoderm® Hypogonadism
12 Lidocaine + Epinephrine Lidosite® Reservoir, Iontophoretic Dermal anastesi

 

 

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